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CME QUIZ
Year : 2020  |  Volume : 18  |  Issue : 1  |  Page : 68-71

Corticobasal degeneration presenting with primary progressive aphasia


Department of Neurology, Federal University of Santa Maria, Santa Maria, Rio Grande do Sul, Brazil

Date of Submission15-Sep-2019
Date of Decision17-Oct-2019
Date of Acceptance22-Oct-2019
Date of Web Publication03-Feb-2020

Correspondence Address:
Mr. Jamir Pitton Rissardo
Av. Roraima n° 1000, Cidade Universitária, Bairro Camobi, Santa Maria - RS 97105-900
Brazil
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/cmi.cmi_41_19

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How to cite this article:
Rissardo JP, Caprara AL. Corticobasal degeneration presenting with primary progressive aphasia. Curr Med Issues 2020;18:68-71

How to cite this URL:
Rissardo JP, Caprara AL. Corticobasal degeneration presenting with primary progressive aphasia. Curr Med Issues [serial online] 2020 [cited 2020 Jul 6];18:68-71. Available from: http://www.cmijournal.org/text.asp?2020/18/1/68/277521




  Case Scenario Top


A 55-year-old female presenting with difficulty hearing and speaking was admitted to our hospital. Her family history was negative for neurological disorders. Although she could perform household activities and her daily habits and personality did not change, her language ability gradually deteriorated over the years. On neurological examination, agrammatic speech with impaired sentence comprehension relatively preserved single-word comprehension, and possible apraxia of speech was observed. Furthermore, her left superior limb was rigidity the right was normal. Laboratory tests were within normal limits. A brain magnetic resonance imaging (MRI) was requested [Figure 1].
Figure 1: Axial T1-weighted (a), axial fluid-attenuated inversion recovery (b), axial T2-weighted gradient-echo (c), coronal T2-weighted (d), and sagittal fluid-attenuated inversion recovery (e and f) images of the brain MRI

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  Questions Top


  1. What are the findings in the brain MRI?
  2. What is the most likely diagnosis taking into account this clinical scenario?




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Declaration of patient consent

The authors certify that they have obtained all appropriate patient consent forms. In the form the patient(s) has/have given his/her/their consent for his/her/their images and other clinical information to be reported in the journal. The patients understand that their names and initials will not be published and due efforts will be made to conceal their identity, but anonymity cannot be guaranteed.

Financial support and sponsorship

Nil.

Conflicts of interest

There are no conflicts of interest.



 
  References Top

1.
Armstrong MJ, Litvan I, Lang AE, Bak TH, Bhatia KP, Borroni B, et al. Criteria for the diagnosis of corticobasal degeneration. Neurology 2013;80:496-503.  Back to cited text no. 1
    
2.
Chan JL, Liu AB. Anatomical correlates of alien hand syndromes. Neuropsychiatry Neuropsychol Behav Neurol 1999;12:149-55.  Back to cited text no. 2
    


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