Home About us Editorial board Ahead of print Current issue Search Archives Submit article Instructions Subscribe Contacts Login 
REVIEW ARTICLE
Year : 2020  |  Volume : 18  |  Issue : 2  |  Page : 98-104

Postmenopausal osteoporosis – An Indian perspective


Department of Endocrinology and Metabolism, Christian Medical College, Vellore, Tamil Nadu, India

Correspondence Address:
Dr. Thomas V Paul
Department of Endocrinology and Metabolism, Christian Medical College, Vellore - 632 004, Tamil Nadu
India
Login to access the Email id

Source of Support: None, Conflict of Interest: None


DOI: 10.4103/cmi.cmi_5_20

Rights and Permissions

Osteoporosis is the most common metabolic bone disease in humans. It is more common in women and contributes to significant morbidity and mortality. Postmenopausal osteoporosis is due to the withdrawal of the protective effect of estrogen at menopause and increased follicle-stimulating hormone, all contributing to increased bone resorption. Evaluation of osteoporosis involves assessment of risk factors, biochemical evaluation, assessment of bone mineral density (BMD) using dual-energy X-ray absorptiometry (DXA), identification of vertebral fractures with vertebral fracture assessment tool, and prediction of fracture risk with various tools. Treatment includes prevention of osteoporosis using lifestyle modification and fall prevention, in addition to pharmacotherapy. Several drugs are licensed to reduce fracture risk namely anti-resorptive agents (such as bisphosphonates and denosumab) and anabolic agents (such as teriparatide). Improved understanding of the cellular basis for osteoporosis has resulted in new drugs targeted to key pathways in the pathogenesis. The response to treatment is monitored using bone turnover markers as well as DXA scan.


[FULL TEXT] [PDF]*
Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed157    
    Printed4    
    Emailed0    
    PDF Downloaded48    
    Comments [Add]    

Recommend this journal