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Year : 2017  |  Volume : 15  |  Issue : 2  |  Page : 131-135

Langerhans cell histiocytosis involving the liver

1 Department of Medicine, CMC, Vellore, Tamil Nadu, India
2 Department of Pathology, University of Michigan, USA
3 Department of Geriatrics, CMC, Vellore, Tamil Nadu, India

Correspondence Address:
Ramya Iyyadurai
Department of Medicine, Christian Medical College, Vellore - 632 004, Tamil Nadu
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/cmi.cmi_19_17

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Langerhans cell histiocytosis is a group of disorders caused by proliferation of the histiocytes. This is a rare neoplastic disease with multisystem involvement. We present a case of an adult male with intermittent fever, recurrent jaundice suggestive of predominant liver involvement. He had undergone multiple courses of anti-tuberculosis treatment with no improvement. Biopsy of the lymph node in our hospital showed Langerhan's cell histiocytosis and liver biopsy showed bridging fibrosis. This case report highlights liver involvement in Langerhans cell histiocytosis with lung and lymph node involvement occurring later, which is an uncommon presentation of this rare disease.

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