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Year : 2020  |  Volume : 18  |  Issue : 4  |  Page : 309-311

Role of tranexamic acid in trauma: Recent updates


Department of Emergency Medicine, Christian Medical College, Vellore, Tamil Nadu, India

Correspondence Address:
Dr. Sandeep Nathanael David
Department of Emergency Medicine, Christian Medical College, Vellore - 632 004, Tamil Nadu
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/cmi.cmi_26_20

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Tranexamic acid (TXA) is a wonder drug in the acute management of hemorrhage in trauma. Recent publication of the CRASH-3 trial results further exemplifies this drug's use in isolated head injury. This article is a review of scientific evidence for TXA in trauma. There is an established role of TXA in trauma with intracranial hemorrhage within 3 h of presentation with 1.5% decrease in mortality of trauma victims with isolated head injury, as per the results of the CRASH-3 trial. However, the optimal dosing and role of the second dose of TXA requires further verification.


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